| Description | Sulisatin is a laxative drug. It is hydrolyzed in the large intestine by the intestinal flora to its diphenyl derivative, BHMI, which is responsible for the laxative activity of the drug. |
| Synonyms | DAN 603, Laxitex, DAN603, Sulisatinum, DAN-603 |
| molecular weight | 491.49 |
| Molecular formula | C21H17NO9S2 |
| CAS | 54935-03-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Moretó M, Goñalons E, Mylonakis N, Giráldez A, Torralba A. 3,3-Bis-(4-hydroxyphenyl)-7-methyl-2-indolinone (BHMI), the active metabolite of the laxative sulisatin. Arzneimittelforschung. 1979;29(10):1561-4. PubMed PMID: 583222. 2. Moretó M, Goñalons E, Giráldez A, Torralba A. Fate and excretion of sodium sulisatin in the rat. Arch Farmacol Toxicol. 1982 Apr;8(1):21-8. PubMed PMID: 7138083. 3. Moretó M, Goñalons E, Mylonakis N, Giräldez A, Torralba A. Enterohepatic circulation of sodium sulisatin and its effects on glucose absorption in the rat. J Pharm Pharmacol. 1977 Jul;29(7):446-8. PubMed PMID: 19589. |