| Description | STING agonist-30 is a potent STING agonist that triggers STING-dependent immune activation.STING agonist-30 shows broad-spectrum inhibitory effects against a variety of viruses including HSV (Herpes Simplex Virus), rotavirus, and SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2). |
| In vitro | 在 Ht1080、Thp1、Bmdms 和 Mefs 细胞中。STING agonist-30 ( 2.5、5、10、20 μ M; 5 h)可诱导出明显的二聚体 STING 条带。 |
| molecular weight | 380.31 |
| Molecular formula | C15H16N4O8 |
| CAS | 2951078-67-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Zang R, et al. Design and syntheses of a bimolecular STING agonist based on the covalent STING antagonist. Eur J Med Chem. 2023 Mar 15;250:115184. |