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STING agonist-1

CAS No.: 702662-50-8

STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.
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Description STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.
Target activity VEEV:24.57 μM (IC90)
Synonyms G10
molecular weight 430.88
Molecular formula C21H16ClFN2O3S
CAS 702662-50-8
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 100 mg/mL (232.08 mM), Sonication is recommended.
References 1. Sali TM, et al. Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses. PLoS Pathog. 2015 Dec 8;11(12):e1005324.
Citations 1. Wang Y, He X, Xue M, et al.Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy.Free Radical Research.2023 (just-accepted): 1-36.