Description | STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation. |
Target activity | STING:185 nM (EC50) |
molecular weight | 490.88 |
Molecular formula | C25H19ClF4N2O2 |
CAS | 2259624-71-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 50 mg/mL (101.86 mM) |