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STING activator Compound 53

CAS No.: 2259624-71-8

STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of S
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Description STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation.
Target activity STING:185 nM (EC50)
molecular weight 490.88
Molecular formula C25H19ClF4N2O2
CAS 2259624-71-8
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 50 mg/mL (101.86 mM)