| Description | STA 2 is an analogue of TXA2, a thromboxane receptor in the colonic epithelium. |
| Synonyms | ONO 11113, STA-2, STA2 |
| molecular weight | 366.56 |
| Molecular formula | C21H34O3S |
| CAS | 89617-02-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Altin JG, Bygrave FL. Prostaglandin F2 alpha and the thromboxane A2 analogue ONO-11113 stimulate Ca2+ fluxes and other physiological responses in rat liver. Further evidence that prostanoids may be involved in the action of arachidonic acid and platelet-activating factor. Biochem J. 1988 Feb 1;249(3):677-85. PubMed PMID: 3128268; PubMed Central PMCID: PMC1148760. 2. Block DH, Shapira M. GATA transcription factors as tissue-specific master regulators for induced responses. Worm. 2015 Nov 30;4(4):e1118607. doi: 10.1080/21624054.2015.1118607. eCollection 2015 Oct-Dec. Review. PubMed PMID: 27123374; PubMed Central PMCID: PMC4826149. 3. Fujioka M, Nagao T, Kuriyama H. Actions of the novel thromboxane A2 antagonists, ONO-1270 and ONO-3708, on smooth muscle cells of the guinea-pig basilar artery. Naunyn Schmiedebergs Arch Pharmacol. 1986 Dec;334(4):468-74. PubMed PMID: 3821937. 4. Lee TM, Charng MJ, Tseng CD, Lai LP. A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of STA-2 (Green Tea Polyphenols) in Patients with Chronic Stable Angina. Acta Cardiol Sin. 2016 Jul;32(4):439-49. PubMed PMID: 27471357; PubMed Central PMCID: PMC4963420. |