| Description | ST271 is an effective protein tyrosine kinase (PTK) inhibitor. |
| In vitro | 由FcγRII交联诱导的肌醇磷酸盐的形成,被ST271 (100 μM) 所抑制。 |
| Target activity | PTK(fMet-Leu-Phe):6.7μM, PTK(PAF):9 μM |
| Synonyms | ST 271 |
| molecular weight | 272.34 |
| Molecular formula | C16H20N2O2 |
| CAS | 106392-48-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (183.59 mM) |
| References | 1. Martinson EA, et al. Inhibition of phospholipase D of human platelets by protein tyrosine kinase inhibitors. Cell Mol Biol (Noisy-le-grand). 1994 Jul;40(5):627-34. 2. Blake RA, et al. Fc gamma receptor II stimulated formation of inositol phosphates in human platelets is blocked by tyrosine kinase inhibitors and associated with tyrosine phosphorylation of the receptor. |