PeptideDB

ST271

CAS No.: 106392-48-7

ST271 is an effective protein tyrosine kinase (PTK) inhibitor.
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Description ST271 is an effective protein tyrosine kinase (PTK) inhibitor.
In vitro 由FcγRII交联诱导的肌醇磷酸盐的形成,被ST271 (100 μM) 所抑制。
Target activity PTK(fMet-Leu-Phe):6.7μM, PTK(PAF):9 μM
Synonyms ST 271
molecular weight 272.34
Molecular formula C16H20N2O2
CAS 106392-48-7
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 50 mg/mL (183.59 mM)
References 1. Martinson EA, et al. Inhibition of phospholipase D of human platelets by protein tyrosine kinase inhibitors. Cell Mol Biol (Noisy-le-grand). 1994 Jul;40(5):627-34. 2. Blake RA, et al. Fc gamma receptor II stimulated formation of inositol phosphates in human platelets is blocked by tyrosine kinase inhibitors and associated with tyrosine phosphorylation of the receptor.