| Description | 1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. 2. Spinosin exerts anxiolytic-like effects, and its mechanism of action appears to be modulated by GABAA and 5-HT1A receptors. 3. There was a wide brain regional tissue distribution of Spinosin. The concentrations of Spinosin in corpus striatum and hippocampus were higher than that in other areas. |
| Synonyms | 斯皮诺素, Flavoayamenin |
| molecular weight | 608.54 |
| Molecular formula | C28H32O15 |
| CAS | 72063-39-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | Ethanol: Soluble DMSO: 91 mg/mL (149.5 mM) Pyridine, Methanol, etc.: Soluble |
| References | 1. Jung I H , Lee H E , Park S J , et al. Ameliorating effect of spinosin, a C-glycoside flavonoid, on scopolamine-induced memory impairment in mice[J]. Pharmacology Biochemistry and Behavior, 2014, 120:88-94. |