| Description | Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1. |
| In vitro | The antiviral activities of two saponins, soyasaponin I and II, isolated from soybean (Glycine max Merrill) were studied in vitro against herpes simplex virus type 1 (HSV-1). Soyasaponin II was more potent than soyasaponin I as shown by reduction of HSV-1 production. Soyasaponin II was also found to inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1. |
| Target activity | HCMV:104 μM (IC50), HIV-1:112 μM (IC50), HSV1:54 μM (IC50), Influenza virus:88 μM (IC50) |
| molecular weight | 913.1 |
| Molecular formula | C47H76O17 |
| CAS | 55319-36-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Inhibitory activity of soyasaponin II on virus replication in vitro. Planta Med., 1997, 63(2):102-5. |