| Description | Sodium 2-oxopropanoate (Sodium pyruvate) is a antioxidant potentially used to treatment of chronic obstructive pulmonary disease. |
| In vivo | Sodium pyruvate nasal spray was effective in attenuating the rhinoconjunctivitis symptoms and reducing the rescue medication use of allergic rhinitis patients[1]. |
| Animal experiments | In the pollen season, all the participants were given corticosteroid nasal spray of standard dose for two weeks, and during the next two weeks they were randomized to treatment group (n = 23) taking nasal sodium pyruvate, and control group (n = 30) without sodium pyruvate.?Daily rhinoconjunctivitis symptom score and daily rescue medication score were analyzed.?Also the fraction of exhaled nitric oxide of the upper airway was measured before and after the treatment of sodium pyruvate[1]. |
| Synonyms | Sodium pyruvate, 丙酮酸钠 |
| molecular weight | 110.04 |
| Molecular formula | C3H3NaO3 |
| CAS | 113-24-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 1.1 mg/mL (10 mM), Sonication is recommended. |
| References | 1. L, S, Li, et al. [Treatment effect of sodium pyruvate nasal spray on allergic rhinitis].[J]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2017. 2. Katharina, Effenberger-Neidnicht, Stephan, et al. Protective Effects of Sodium Pyruvate during Systemic Inflammation Limited to the Correction of Metabolic Acidosis.[J]. Inflammation, 2018. |