| Description | SLLK, Control Peptide for TSP1 Inhibitor acetate is a control peptide for LSKL. |
| In vivo | 在接受LSKL处理的小鼠群体中，TGF-β1在血浆中的浓度显著低于接受SLLK对照肽处理的小鼠群体，42天时的数据分别为0.10±0.01 pg/mL与0.20±0.02 pg/mL（P=0.0001）。mRNA表达量在接受SLLK与LSKL肽处理小鼠所获得的肾上腺主动脉裂解液中进行了评估[1]。接受30 mg/kg LSKL处理的Akita小鼠的nephrin表达量显著增加，与接受生理盐水对照组或SLLK处理的小鼠的肾脏裂解物相比，增加了两倍以上[2]。 |
| Synonyms | SLLK, Control Peptide for TSP1 Inhibitor acetate(464924-27-4,free base) |
| molecular weight | 518.66 |
| Molecular formula | C23H46N6O7 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 10 mM |
| References | 1. Krishna SM, et al. A peptide antagonist of thrombospondin-1 promotes abdominal aortic aneurysm progression in the angiotensin II-infused apolipoprotein-E-deficient mouse. Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):389-98. |