| Description | SIRT5 Inhibitor 5 is a potent substrate-competitive inhibitor of SIRT5, exhibiting an IC50 of 0.21 µM, and does not interact with the NAD+-binding pocket [1]. |
| In vitro | SIRT5抑制剂5（化合物47）（0-10 µM）在NAD+（50, 100, 200, 400, 800 µM）不同浓度下的抑制效果无显著差异，而在Ac-K(Suc)-AMC（10、30、90、270 µM）浓度升高时抑制效果有所降低[1]。 |
| Target activity | SIRT5:0.21 μM |
| molecular weight | 423.87 |
| Molecular formula | C21H14ClN3O3S |
| CAS | 2883730-60-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |