| Description | Sibeprenlimab (VIS649) is a humanized IgG 2 monoclonal antibody that suppresses APRIL. Sibeprenlimab has an inhibitory effect on APRIL and may be studied for the prevention and treatment of kidney disease (IgAN). |
| Synonyms | VIS649, VIS-649 |
| molecular weight | N/A |
| CAS | 2382896-07-1 |
| Storage | store at low temperature | store at -80°C |
| References | 1. Mohit Mathur, et al. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VIS649 (Sibeprenlimab), an APRIL-Neutralizing IgG2 Monoclonal Antibody, in Healthy Volunteers. Kidney Int Rep. 2022 Feb 8;7(5):993-1003. |