PeptideDB

Clivatuzumab

CAS No.: 1622075-09-5

Clivatuzumab is a humanized anti-myxinomab, which can target the MUC1 epitope highly expressed on the surface of most pa
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Description Clivatuzumab is a humanized anti-myxinomab, which can target the MUC1 epitope highly expressed on the surface of most pancreatic cancer cells, and has a good therapeutic effect on a variety of tumor cells.
In vitro Clivatuzumab 对胰腺导管腺癌(PDAC)表现出高度特异性,对正常及良性的非肿瘤胰腺组织几乎不表现出反应。尽管它对其他某些器官(如胃、结肠和肺)的腺癌反应有限(大约10%的样本)[1]。
molecular weight N/A
CAS 1622075-09-5
Storage store at low temperature | store at -80°C
References 1. Gold DV, et al. Mapping PAM4 (clivatuzumab), a monoclonal antibody in clinical trials for early detection and therapy of pancreatic ductal adenocarcinoma, to MUC5AC mucin. Mol Cancer. 2013 Nov 20;12(1):143.