| Description | Sel-green is a selective selenol fluorescent probe used for quantifying the selenocysteine (Sec) content in the selenoenzyme thioredoxin reductase, as well as imaging endogenous Sec in live HepG2 cells. |
| In vitro | Sel-green displays >20-fold selectivity of Sec over DTT[1]. Sel-green is suitable for identifying the selenol species metabolized from various selenocompounds in cells, which helps to clarify the mechanism underlying the cytotoxicity of different selenocompounds[1]. |
| molecular weight | 462.43 |
| Molecular formula | C19H18N4O8S |
| CAS | 1574299-37-8 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Baoxin Zhang, et al. Selective selenol fluorescent probes: design, synthesis, structural determinants, and biological applications. J Am Chem Soc. 2015 Jan 21;137(2):757-69. |