| Description | SB-1295, an orally active CDK9/T1 inhibitor with an IC50 of 0.17 μM, exhibits antiproliferative effects on HCT 116 and MIA PaCa-2 cells. It promotes cell death in MIA PaCa-2 by elevating intracellular ROS levels, diminishing mitochondrial membrane potential, and triggering apoptosis. This compound holds potential for cancer research [1]. |
| molecular weight | 443.88 |
| Molecular formula | C23H22ClNO6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |