| Description | Sapienic acid sodium is a fatty acid commonly. It has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. |
| In vitro | Sapienic acid 对抗Streptococcus sanguinis、Streptococcus mitis和Fusobacterium nucleatum具有活性。动力学分析表明,sapienic acid是逐渐杀灭S. sanguinis和S. mitis的[1]。 |
| Target activity | Streptococcus sanguinis: 375.0 μg/mL , Fusobacterium nucleatum:, MBC: 31.3 μg/mL , Streptococcus mitis:93.8 μg/mL |
| molecular weight | 276.4 |
| Molecular formula | C16H29NaO2 |
| CAS | 217477-25-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | Ethanol: 0.7 mg/mL (2.57 mM), Sonication is recommended. DMSO: 3.85 mg/mL (13.86 mM), Sonication is recommended. |
| References | 1. Fischer CL, et al. Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria. Antimicrob Agents Chemother. 2012 Mar;56(3):1157-61. |