| Description | (S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM). |
| Target activity | HIV-1 integrase:(EC50)450 nM, HIV-1 integrase:(kd)4.7 μM, HIV-1 integrase:28 nM |
| molecular weight | 420.68 |
| Molecular formula | C19H15BrClNO3 |
| CAS | 957889-73-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Fader LD, et al. Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1. ACS Med Chem Lett. 2014 Jan 22;5(4):422-7. |