| Description | L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata. |
| In vitro | L-γ-Glutamyl-S-[(4-羥基苯基)甲基]能够抑制[3H]海因酸与大脑谷氨酸受体的特异性结合,其半抑制浓度(IC50)为2 μM[1]。与谷氨酸和谷胱甘肽相比,该化合物的亲和力(IC50值)略低。 |
| Target activity | Glutamate receptor:2 μM |
| molecular weight | 413.45 |
| Molecular formula | C17H23N3O7S |
| CAS | 129636-38-0 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/ml (133.03 mM) |
| References | 1. Andersson M, et, al. Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia. Phytochemistry. 1995 Mar;38(4):835-6. |