| Description | RP-101075 is a etabolite of Ozanimod. It exhibits a similar specificity profile as Ozanimod at the S1P receptor family in vitro, and pharmacodynamic profile in vivo. |
| Synonyms | RP101075 |
| molecular weight | 360.42 |
| Molecular formula | C21H20N4O2 |
| CAS | 1306760-73-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Taylor Meadows KR, Steinberg MW, Clemons B, Stokes ME, Opiteck GJ, Peach R, Scott FL. Ozanimod (RPC1063), a selective S1PR1 and S1PR5 modulator, reduces chronic inflammation and alleviates kidney pathology in murine systemic lupus erythematosus. PLoS One. 2018 Apr 2;13(4):e0193236. doi: 10.1371/journal.pone.0193236. eCollection 2018. PubMed PMID: 29608575; PubMed Central PMCID: PMC5880347. |