| Description | Ro0711401 is an agonist of mGlu1 receptor. |
| Target activity | mGluR1:56 nM (EC50) |
| Synonyms | Ro-0711401, Ro 0711401 |
| molecular weight | 360.29 |
| Molecular formula | C18H11F3N2O3 |
| CAS | 714971-87-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 100 mg/mL (277.55 mM), Sonication is recommended. |
| References | 1. D'Amore V, Santolini I, Celli R, Lionetto L, De Fusco A, Simmaco M, van Rijn CM, Vieira E, Stauffer SR, Conn PJ, Bosco P, Nicoletti F, van Luijtelaar G, Ngomba RT. Head-to head comparison of mGlu1 and mGlu5 receptor activation in chronic treatment of absence epilepsy in WAG/Rij rats. Neuropharmacology. 2014 Oct;85:91-103. doi: 10.1016/j.neuropharm.2014.05.005. Epub 2014 May 20. PubMed PMID: 24859611; PubMed Central PMCID: PMC4356528. |