| Description | Ro 22-0654, a novel lipid synthesis inhibitor, has antiobesity effects. |
| Synonyms | Ro-22-0654 |
| molecular weight | 185.24 |
| Molecular formula | C8H11NO2S |
| CAS | 81741-99-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Leinweber FJ, Szuna AJ, Loh AC, Williams TH, Sasso GJ, Bekersky I, Baggiolini E, Triscari J. Metabolism of the anti-obesity agent, 4-amino-5-ethyl-3-thiophenecarboxylic acid methyl ester hydrochloride, in rats and dogs. Xenobiotica. 1987 Dec;17(12):1405-14. PubMed PMID: 3439191. 2. Sullivan AC, Hogan S, Triscari J. New developments in pharmacological treatments for obesity. Ann N Y Acad Sci. 1987;499:269-76. Review. PubMed PMID: 3300486. 3. Stewart IC, Chapman BJ, Munro JF. Pharmacological approaches to the regulation of fat metabolism. Bibl Nutr Dieta. 1986;(39):16-26. PubMed PMID: 3541889. 4. Brooks MA, Lee TL. Determination of 4-amino-5-ethyl-3-thiophenecarboxylic acid methyl ester and its acid metabolite in plasma and urine by high-performance liquid chromatography. J Chromatogr. 1985 Dec 13;345(2):333-43. PubMed PMID: 4086602. |