RO-09-4609 Bioactivity,Chemical Properties,Storage & Solubility Information Pathways-PeptideDB

Description	RO-09-4609 is a potent and selective inhibitor of Candida albicans N-myristoyltransferase (CaNmt).
Synonyms	RO 09-4609, RO09-4609, RO 094609, RO-094609
molecular weight	368.43
Molecular formula	C21H24N2O4
CAS	279230-20-5
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
References	1. Masubuchi M, Ebiike H, Kawasaki K, Sogabe S, Morikami K, Shiratori Y, Tsujii S, Fujii T, Sakata K, Hayase M, Shindoh H, Aoki Y, Ohtsuka T, Shimma N. Synthesis and biological activities of benzofuran antifungal agents targeting fungal N-myristoyltransferase. Bioorg Med Chem. 2003 Oct 1;11(20):4463-78. PubMed PMID: 13129583. 2. Ebiike H, Masubuchi M, Liu P, Kawasaki K, Morikami K, Sogabe S, Hayase M, Fujii T, Sakata K, Shindoh H, Shiratori Y, Aoki Y, Ohtsuka T, Shimma N. Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 2. Bioorg Med Chem Lett. 2002 Feb 25;12(4):607-10. PubMed PMID: 11844682. 3. Masubuchi M, Kawasaki K, Ebiike H, Ikeda Y, Tsujii S, Sogabe S, Fujii T, Sakata K, Shiratori Y, Aoki Y, Ohtsuka T, Shimma N. Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 1. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1833-7. PubMed PMID: 11459642.

PeptideDB