| Description | NSC624206 is a ubiquitin E1 (UBA1) inhibitor(IC50 of ~9 μM). |
| In vitro | NSC624206 (10 nM-10 μM; 24 hours) induces accumulation of p27 in cells[1]. |
| Target activity | Ubiquitin E1:~9 μM |
| molecular weight | 410.51 |
| Molecular formula | C19H33Cl2NS2 |
| CAS | 13116-77-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Dana Ungermannova, et al. Identification and Mechanistic Studies of a Novel Ubiquitin E1 Inhibitor. J Biomol Screen . 2012 Apr;17(4):421-34. |