| Description | Ricinine (1,2-Dihydro-4-methoxy-1-methyl-2-oxonicotinonitrile) is a major alkaloid in Ricinus communis plant with hepatoprotection in CCl4 -induced liver damage. |
| Synonyms | 1,2-Dihydro-4-methoxy-1-methyl-2-oxonicotinonitrile, 蓖麻碱, Ricinin, Ritsinin |
| molecular weight | 164.16 |
| Molecular formula | C8H8N2O2 |
| CAS | 524-40-3 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 4.8 mg/mL (29.24 mM) |
| References | 1. El-Naggar MH, et al. Antimicrobial and antiquorum-sensing activity of Ricinus communis extracts and ricinine derivatives. Nat Prod Res. 2018 Jan 15:1-7. 2. Marwat SK, et al. Review - Ricinus cmmunis - Ethnomedicinal uses and pharmacological activities. Pak J Pharm Sci. 2017 Sep;30(5):1815-1827. 3. Oriakhi K, et al. Isolation, characterization, and hepatoprotective properties of betulinic acid and ricinine from Tetracarpidium conophorum seeds (Euphorbiaceae). J Food Biochem. 2021;45(3):e13288. 4. Xu W, et al. Optimization of Ultrasonic-Microwave Synergistic Extraction of Ricinine from Castor Cake by Response Surface Methodology. Curr Pharm Biotechnol. 2016;17(13):1126-1133. |