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Eliglustat hemitartrate

CAS No.: 928659-70-5

Eliglustat hemitartrate (Genz-112638) , with an IC50 of 24 nM, is a specific, potent, oral active glucocerebral glycosid
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Description Eliglustat hemitartrate (Genz-112638) , with an IC50 of 24 nM, is a specific, potent, oral active glucocerebral glycosidase inhibitor.
In vitro Eliglustat tartrate 对目标酶表现出良好的效能,其IC50值为24 nM,并且具有特异性。
Target activity Glucocerebroside synthase:24 nM
Synonyms Genz-112638, 依利格鲁司特酒石酸盐, Eliglustat tartrate
molecular weight 959.17
Molecular formula C50H78N4O14
CAS 928659-70-5
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility H2O: 50 mg/mL (52.13 mM) DMSO: 50 mg/mL (52.13 mM)
References 1. McEachern KA, et al. A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy ofGaucher disease. Mol Genet Metab. 2007 Jul;91(3):259-67.