| Description | Eliglustat hemitartrate (Genz-112638) , with an IC50 of 24 nM, is a specific, potent, oral active glucocerebral glycosidase inhibitor. |
| In vitro | Eliglustat tartrate 对目标酶表现出良好的效能,其IC50值为24 nM,并且具有特异性。 |
| Target activity | Glucocerebroside synthase:24 nM |
| Synonyms | Genz-112638, 依利格鲁司特酒石酸盐, Eliglustat tartrate |
| molecular weight | 959.17 |
| Molecular formula | C50H78N4O14 |
| CAS | 928659-70-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: 50 mg/mL (52.13 mM) DMSO: 50 mg/mL (52.13 mM) |
| References | 1. McEachern KA, et al. A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy ofGaucher disease. Mol Genet Metab. 2007 Jul;91(3):259-67. |