| Description | Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ß (HPTPß) inhibitor (IC50: 50 nM). Razuprotafib is effective for the activation of Tie-2 and is protective against acute kidney injury. |
| Target activity | HPTPß:50 nM |
| Synonyms | AKB-9778 |
| molecular weight | 586.7 |
| Molecular formula | C26H26N4O6S3 |
| CAS | 1008510-37-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 100 mg/mL (170.44 mM), Sonication is recommended. |
| References | 1. Kevin Peters, et al. METHODS OF TREATING DIABETIC NEPHROPATHY USING HPTPß INHIBITORS. WO2019165349A1 |