| Description | Raphin1 is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). |
| Target activity | R15B-PP1c holophosphatase:Kd：33 nM |
| molecular weight | 231.08 |
| Molecular formula | C8H8Cl2N4 |
| CAS | 2022961-17-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 125 mg/mL (540.94 mM) |
| References | 1. Krzyzosiak A, Sigurdardottir A, Luh L,et al.Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B.Cell. 2018 Aug 23 ;174(5):1216-1228.e19. |