| Description | PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM) |
| Synonyms | PTP1B inhibitor, 5-苯基-1,2,5-噻二唑烷-3-酮 1,1-二氧化物 |
| molecular weight | 212.23 |
| Molecular formula | C8H8N2O3S |
| CAS | 612530-44-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 38 mg/mL (179.05 mM) |
| References | 1. Wang Y , Yan F , Ye Q , et al. PTP1B inhibitor promotes endothelial cell motility by activating the DOCK180/Rac1 pathway[J]. Scientific Reports, 2016, 6:24111. 2. Black E , Breed J , Breeze A L , et al. Structure-Based Design of Protein Tyrosine Phosphatase-1B Inhibitors[J]. Cheminform, 2005, 15(10):2503-2507. |