| Description | Pyridostigmine(Regonol) is an acetylcholinesterase inhibitor that can treat myasthenia gravis by increasing acetylcholine at the postsynaptic motor endplate. |
| In vivo | Pyridostigmine具有治疗SSc患者多种胃肠道症状的潜力，特别是对于那些患有难治性便秘的患者。虽然副作用可能限制其使用，但大多数获益的患者选择继续治疗[1]。 |
| Synonyms | Regonol, Mestinon-SR, UNII-19QM69HH21, PyridostigmineBromine, Pyridostigminum |
| molecular weight | 181.21 |
| Molecular formula | C9H13N2O2 |
| CAS | 155-97-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 25 mg/mL (95.74 mM) |
| References | 1. Ahuja N K , Mische L , Clarke J O , et al. Pyridostigmine for the treatment of gastrointestinal symptoms in systemic sclerosis[J]. Semin Arthritis Rheum, 2018:S0049017217305498. 2. Byun J I , Moon J , Kim D Y , et al. Efficacy of single or combined midodrine and pyridostigmine in orthostatic hypotension[J]. Neurology, 2017:10.1212/WNL.0000000000004340. |