| Description | PSN 375963 hydrochloride, a potent GPR119 agonist, demonstrates EC50 values of 8.4 μM and 7.9 μM for human and mouse GPR119, respectively. Its efficacy is comparable to that of the endogenous agonist oleoylethanolamide (OEA) [1] [2]. |
| In vitro | The endogenous ligand OEA signals via GPR119 in a manner similar to glucagon-like peptide-1 (GLP-1) and its receptor with respect to insulin secretion, intracellular calcium and cAMP [2]. |
| molecular weight | 321.85 |
| Molecular formula | C17H24ClN3O |
| CAS | 1781834-82-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
PSN 375963 hydrochloride（388575-52-8 Free base）
CAS No.: 1781834-82-9
PSN 375963 hydrochloride, a potent GPR119 agonist, demonstrates EC50 values of 8.4 μM and 7.9 μM for human and mouse G
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