| Description | Protohypericin, a naphthodianthrone derivative found in the plant Hypericum perforatum, exhibits photocytotoxicity and is utilized in tumor necrosis targeted radiotherapy through its radioiodinated form. |
| In vitro | 实验在特定的过滤光条件下进行,以防止Protohypericin的非预期光转换和细胞的光敏化。通过评估照射时间对光细胞性毒性的影响,发现两种化合物的光细胞性毒性在长时间照射后(即15分钟)趋于一致,而在短时间照射(即1分钟)后,光细胞性毒性差异达到最大[1]。 |
| molecular weight | 506.46 |
| Molecular formula | C30H18O8 |
| CAS | 548-03-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: Slightly soluble |
| References | 1. Photocytotoxicity of protohypericin after photoconversion to hypericin.Planta Med. 1999 Dec;65(8):719-22. |