| Description | Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM. |
| In vitro | Prostaglandin G/H synthase 1抑制剂在大鼠肝微粒体测定中抑制D5D，IC50为0.04 μM[2]。 |
| Synonyms | CP74006, CP 74006, 2-Amino-N-(4-chlorophenyl)benzamide |
| molecular weight | 246.69 |
| Molecular formula | C13H11ClN2O |
| CAS | 4943-86-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 50 mg/mL (202.68 mM) |
| References | 1. Zhang L, et al. A multiplexed cell assay in HepG2 cells for the identification of delta-5, delta-6, and delta-9 desaturase and elongase inhibitors. J Biomol Screen. 2010 Feb;15(2):169-76. 2. Obukowicz MG, Welsch DJ, Salsgiver WJ, Martin-Berger CL, Chinn KS, Duffin KL, Raz A, Needleman P. Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. J Pharmacol Exp Ther. 1998 Oct;287(1):157-66. |