PeptideDB

ISRIB-A15

CAS No.: 1628478-12-5

ISRIB-A15 (ISR-IN-2) is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM.
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Description ISRIB-A15 (ISR-IN-2) is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM.
Synonyms ISR-IN-2
molecular weight 520.23
Molecular formula C22H22Cl4N2O4
CAS 1628478-12-5
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: Insoluble H2O: Insoluble
References 1. Hearn BR, et al. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19;11(8):870-80.