| Description | Platicodigenin (Platycodigenin) isolated from platycodon grandiflorum, has in vitro anti-proliferative activity against the HSC-T6 cell line. |
| In vitro | 从桔梗(Platycodon grandiflorum)的根中分离得到两种新的齐墩果烷型三萜类化合物，命名为platycodonoids A和B(1, 2)，以及五种已知的皂苷，包括platycodin D(3)、deapioplatycodin D(4)、3-O-β-D-葡萄糖吡喃苷聚甘草酸(5)、3-O-β-D-葡萄糖吡喃苷Platycodigenin(6)和polygalacin D(7)。通过光谱数据和化学证据确定了新化合物的结构，分别为2β,3β,23,24-四羟基-28-去甲基-齐墩果-12-烯-16-酮(1)和2β,3β,23,24-四羟基-28-去甲基-齐墩果-12-烯-16-酮-3-O-β-D-葡萄糖吡喃苷(2)。化合物1-7对HSC-T6细胞系的体外抗增殖活性进行了评价。 |
| Synonyms | 桔梗皂苷元, Platycodigenin |
| molecular weight | 520.7 |
| Molecular formula | C30H48O7 |
| CAS | 22327-82-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 60 mg/mL (115.23 mM) |
| References | 1. Two new oleanane-type triterpenoids from Platycodi Radix and anti-proliferative activity in HSC-T6 cells. Molecules. 2012 Dec 13;17(12):14899-907. |