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PKC-theta inhibitor hcl

CAS No.: 2253640-49-0

PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).
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Description PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).
Target activity PKCθ:12 nM
Synonyms PKC-theta inhibitor
molecular weight 490.91
Molecular formula C20H26ClF3N6O3
CAS 2253640-49-0
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 55 mg/mL (121.04 mM), Sonication is recommended.
References 1. Cywin C L , Dahmann G , Iii A S P , et al. Discovery of potent and selective PKC-θ inhibitors[J]. Bioorganic & Medicinal Chemistry Letters, 2007, 17(1):225-230.