| Description | PIK-293 is a PI3K inhibitor, for PI3Kδ( IC50=0.24 μM), and less potent for PI3Kα/β/ γ. |
| In vitro | PIK-293 is a pyrazolopyrimidine analog of IC87114. PIK-293 is synthesized by replacing the adenine of IC87114 with the isosteric pyrazolopyrimidine. [1] |
| Target activity | PI3Kδ:0.24 μM |
| Synonyms | PIK293 |
| molecular weight | 397.43 |
| Molecular formula | C22H19N7O |
| CAS | 900185-01-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 80 mg/mL (201.29 mM) |
| References | 1. Knight ZA et al. Cell, 2006, 125(4), 733-747. |