| Description | PI3K-IN-48, a PI3K inhibitor, exhibits an IC50 of 1.55 ± 0.18 μM in A549 cells, demonstrating its potency in this context. It induces G0/G1 phase arrest and cell apoptosis, while also down-regulating the expression of p-PI3K and p-Akt. This compound is relevant for research into the treatment of human lung cancers [1]. |
| molecular weight | 432.44 |
| Molecular formula | C25H21FN2O4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |