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PF-4479745

CAS No.: 1065110-43-1

PF-4479745 ia a potent and selective agonist of 5-HT2C receptor.
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Description PF-4479745 ia a potent and selective agonist of 5-HT2C receptor.
molecular weight 282.38
Molecular formula C17H22N4
CAS 1065110-43-1
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Storer RI, Brennan PE, Brown AD, Bungay PJ, Conlon KM, Corbett MS, DePianta RP, Fish PV, Heifetz A, Ho DK, Jessiman AS, McMurray G, de Oliveira CA, Roberts LR, Root JA, Shanmugasundaram V, Shapiro MJ, Skerten M, Westbrook D, Wheeler S, Whitlock GA, Wright J. Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HT₂C) receptor agonists with exquisite functional selectivity over 5-HT₂A and 5-HT₂B receptors. J Med Chem. 2014 Jun 26;57(12):5258-69. doi: 10.1021/jm5003292. Epub 2014 Jun 17. PubMed PMID: 24878222.