| Description | Persicogenin has anticancer, antimutagenic, and antileishmanial activities, it can inhibit the proliferation of mouse tsFT210 cancer cells, it mainly inhibits cell cycle at the G2/M phase in a dose-dependent manner. |
| In vitro | 化合物1对结核分枝杆菌(Mycobacterium tuberculosis)表现出中等的抗菌活性,其最小抑菌浓度(MIC)值为174.8微摩尔;而化合物4、7和8对该菌株的活性较弱,其MIC值分别为606.0、704.2和699.3微摩尔。化合物7对人类小细胞肺癌(NCI-H187)细胞展现中等的细胞毒性,MIC值为24.6微摩尔;化合物8对NCI-H187细胞表现中等毒性,并对人类乳腺癌(BC)细胞表现出较弱的毒性,其MIC值分别为19.2和38.4微摩尔[1]。 |
| molecular weight | 316.309 |
| Molecular formula | C17H16O6 |
| CAS | 28590-40-1 |
| Storage | store at low temperature|Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/ml (189.69 mM), Sonication is recommended. |
| References | 1. Antimycobacterial activity and cytotoxicity of flavonoids from the flowers of Chromolaena odorata.Arch Pharm Res. 2004 May;27(5):507-11. |