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Persicogenin

CAS No.: 28590-40-1

Persicogenin has anticancer, antimutagenic, and antileishmanial activities, it can inhibit the proliferation of mouse ts
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Description Persicogenin has anticancer, antimutagenic, and antileishmanial activities, it can inhibit the proliferation of mouse tsFT210 cancer cells, it mainly inhibits cell cycle at the G2/M phase in a dose-dependent manner.
In vitro 化合物1对结核分枝杆菌(Mycobacterium tuberculosis)表现出中等的抗菌活性,其最小抑菌浓度(MIC)值为174.8微摩尔;而化合物4、7和8对该菌株的活性较弱,其MIC值分别为606.0、704.2和699.3微摩尔。化合物7对人类小细胞肺癌(NCI-H187)细胞展现中等的细胞毒性,MIC值为24.6微摩尔;化合物8对NCI-H187细胞表现中等毒性,并对人类乳腺癌(BC)细胞表现出较弱的毒性,其MIC值分别为19.2和38.4微摩尔[1]。
molecular weight 316.309
Molecular formula C17H16O6
CAS 28590-40-1
Storage store at low temperature|Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 60 mg/ml (189.69 mM), Sonication is recommended.
References 1. Antimycobacterial activity and cytotoxicity of flavonoids from the flowers of Chromolaena odorata.Arch Pharm Res. 2004 May;27(5):507-11.