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Pep 2-8 ammonium salt(1541011-97-5 free base)

CAS No.:

Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 bind
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Description Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
molecular weight 1732.91
Molecular formula C83H113N17O24
Storage keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 10 mM
References 1. Zhang et al (2014) Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor. J.Biol.Chem. 289 942 PMID: