| Description | PDDC inhibitor (Phenyl (R)-(1-(3-(3,4-dimethoxyphenyl)-2,6-dimethylimidazo[1,2-b]pyridazin-8-yl)pyrrolidin-3-yl)carbamate) is a selective and highly potent nSMase2 inhibitor. |
| molecular weight | 487.55 |
| Molecular formula | C27H29N5O4 |
| CAS | 2232878-43-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Siew ZY, et al. Fighting nature with nature: antiviral compounds that target retroviruses. Arch Microbiol. 2024 Feb 28;206(3):130. 2. Moloudizargari M, et al. Virtual screening reveals aprepitant to be a potent inhibitor of neutral sphingomyelinase 2: implications in blockade of exosome release in cancer therapy. J Cancer Res Clin Oncol. 2023 Aug;149(10):7207-7216. |