| Description | Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist. |
| In vitro | Pancreatic Polypeptide (human) acetate(hPP)是一种特殊的肽，其释放依赖于卡路里摄入、食物消耗和昼夜节律，由胰岛F细胞在餐后释放。该肽为一种具有特征性发夹状胰高血糖肽(PP)折叠的C末端酰胺化的36氨基酸肽，通过作用于Y4受体来诱导饱腹感、延迟胃排空和减缓胃肠蠕动[1]。添加Pancreatic Polypeptide (human) acetate(hPP)（10 nM-1 μM）能够显著且剂量依赖性地减少基础和刺激后的释放。Pancreatic Polypeptide (human) acetate(hPP)还能抑制基础和刺激后的NPY释放，其药理学特性表明Y4突触前受体的作用[2]。 |
| molecular weight | N/A |
| Storage | keep away from moisture|Powder: -20°C for 3 years | In solvent: -80°C for 1 year |