| Description | Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is an agonist of toll-like receptor 1/2 (TLR1/2) (EC50 of 0.47 ng/mL for human TLR1/2). |
| In vitro | Pam3CSK4是一种能够识别三酰基脂肽的TLR1/2异源二聚体[1]。研究发现，在TLR2/1激活反应中，Pam2CSK4与Pam3CSK4之间存在种属差异。在1 μg/mL的浓度下，Pam3CSK4能够增强经由粒细胞巨噬细胞集落刺激因子（GM-CSF）激活的中性粒细胞对抗甲氧西林抗性金黄色葡萄球菌（MRSA）的抗菌功能[2]。 |
| Synonyms | Pam3CSK4 TFA, Pam3Cys-Ser-(Lys)4 TFA |
| molecular weight | 1852.33 |
| Molecular formula | C87H159F9N10O19S |
| CAS | 112208-01-2 |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: Soluble |
| References | 1. Irvine KL, et al. The molecular basis for recognition of bacterial ligands at equine TLR2, TLR1 and TLR6. Vet Res. 2013 Jul 4;44:50. |
Pam3CSK4 TFA (112208-00-1 free base)
CAS No.: 112208-01-2
Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is an agonist of toll-like receptor 1/2 (TLR1/2) (EC50 of 0.47 ng/mL for human TLR
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.