| Description | P-gp Inhibitor 13, a P-glycoprotein antagonist, can counteract paclitaxel resistance in A2780/T cells, proving valuable for advanced acute myeloid leukemia research [1]. |
| In vitro | P-gp inhibitor 13（Compound 27f）在A2780/T细胞中显著提高了化疗药物的敏感性，IC 50 值达到0.010 μM [1]。该抑制剂能有效增强紫杉醇及罗丹明123的累积，从而逆转多药耐药现象 [1]。此外，P-gp inhibitor 13具有很低的心脏毒性 [1]。在A2780/T细胞中，P-gp inhibitor 13展现了2.5 μM至20 μM浓度范围内的浓度依赖型多药耐药（MDR）逆转活性 [1]。 |
| molecular weight | 546.61 |
| Molecular formula | C32H34O8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |