Description | Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development. |
Synonyms | 2-吲哚酮, 板蓝根, Indolin-2-one |
molecular weight | 133.15 |
Molecular formula | C8H7NO |
CAS | 59-48-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility | DMSO: 16.67 mg/mL (125.17 mM), Sonication is recommended. |