| Description | Oleclumab (MEDI9447), a human IgG1λ monoclonal antibody, targets and inhibits CD73 functionality, demonstrating anti-tumor activity [1]. |
| Synonyms | MED I9447, MEDI9447, MEDI-9447 |
| molecular weight | N/A |
| CAS | 1803176-05-7 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 years | Shipping with blue ice. |
| References | 1. Roy S Herbst, et al. COAST: An Open-Label, Phase II, Multidrug Platform Study of Durvalumab Alone or in Combination With Oleclumab or Monalizumab in Patients With Unresectable, Stage III Non-Small-Cell Lung Cancer. J Clin Oncol. 2022 Apr 22;JCO2200227. 2. Hay CM, et al. Targeting CD73 in the tumor microenvironment with MEDI9447. Oncoimmunology. 2016 Jul 11;5(8):e1208875. |