PeptideDB

NPY 5RA972

CAS No.: 439861-56-0

NPY 5RA972 is a neuropeptide Y Y5 receptor antagonist
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Description NPY 5RA972 is a neuropeptide Y Y5 receptor antagonist
molecular weight 351.44
Molecular formula C21H25N3O2
CAS 439861-56-0
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: < 35.14 mg/mL
References 1. Li P, Tiwari HK, Lin WY, Allison DB, Chung WK, Leibel RL, Yi N, Liu N. Genetic association analysis of 30 genes related to obesity in a European American population. Int J Obes (Lond). 2014 May;38(5):724-9. doi: 10.1038/ijo.2013.140. Epub 2013 Jul 31. PubMed PMID: 23900445; PubMed Central PMCID: PMC3909018. 2. Morris MJ, Gannan E, Stroud LM, Beck-Sickinger AG, O'Brien TJ. Neuropeptide Y suppresses absence seizures in a genetic rat model primarily through effects on Y receptors. Eur J Neurosci. 2007 Feb;25(4):1136-43. PubMed PMID: 17331209. 3. Gabriele B, Salerno G, Mancuso R, Costa M. Efficient synthesis of ureas by direct palladium-catalyzed oxidative carbonylation of amines. J Org Chem. 2004 Jul 9;69(14):4741-50. PubMed PMID: 15230597. 4. Turnbull AV, Ellershaw L, Masters DJ, Birtles S, Boyer S, Carroll D, Clarkson P, Loxham SJ, McAulay P, Teague JL, Foote KM, Pease JE, Block MH. Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats. Diabetes. 2002 Aug;51(8):2441-9. PubMed PMID: 12145156.