| Description | nor-NOHA monoacetate (Nω-Hydroxy-nor-L-arginine) is a highly potent and selective arginase inhibitor. nor-NOHA monoacetate inhibits rat hepatic arginase and inhibits the hydrolysis of L-arginine, which can be used to study cardiovascular and obstructive airway diseases. |
| Synonyms | Nor NOHA monoacetate, Nω-Hydroxy-nor-L-arginine monoacetate |
| molecular weight | 236.23 |
| Molecular formula | C7H16N4O5 |
| CAS | 2250019-93-1 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (211.66 mM), Sonication is recommended. H2O: 40 mg/mL (169.326 mM), Sonication is recommended. |
| References | 1. Custot J, et al. A new α-amino acid N w -hydroxy-nor-L-arginine: A highly-affinity inhibitor of arginase well adapted to bind to its manganese cluster.Journal of the American Chemical Society 119, 4086-4087(1997). 2. Tenu JP, et al. Effects of the new arginase inhibitor N(omega)-hydroxy-nor-L-arginine on NO synthase activity in murine macrophages. Nitric Oxide. 1999;3(6):427-438. |