| Description | Nitrilotriacetic acid (Nitriloacetate) is a chelator that tracks and enriches His-tagged proteins in living cells by reacting with divalent metal ions-mediated 6His tagging. |
| Synonyms | Triglycollamic acid, Nitrilotriacetate, Nitriloacetate |
| molecular weight | 191.14 |
| Molecular formula | C6H9NO6 |
| CAS | 139-13-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 15 mg/mL (78.48 mM), Sonication is recommended. 0.1M NaOH: 15 mg/mL (78.48 mM), Sonication is recommended. |
| References | 1. Abdelazim MH, et al. Effect of intra-nasal nitrilotriacetic acid trisodium salt in lowering elevated calcium cations and improving olfactory dysfunction in COVID-19 patients. Eur Arch Otorhinolaryngol. 2022 Sep;279(9):4623-4628. 2. Zhang S, et al. Exploring the promoting effect of nitrilotriacetic acid on hydroxyl radical and humification during magnetite-amended composting of sewage sludge. Bioresour Technol. 2024 Jul;403:130863. 3. Ivan M, et al. The effects of nitrilotriacetic acid on solubilities of zinc, copper, manganese, and iron in the stomach of sheep. Can J Physiol Pharmacol. 1979 Apr;57(4):369-74. 4. Chatterjee M, et al. Functionalization of hydroxy compounds with nitrilotriacetic acid for technetium-99m chelation: excretory properties of the radiolabelled chelates. Int J Rad Appl Instrum B. 1991;18(3):263-74. |