| Description | Nicotelline, also known as Nicotellin, is an alkaloid associated with nicotine and acts as a modest inhibitor of the enzyme human cDNA-expressed cytochrome P-450 2A6 (CYP2A6), which is responsible for coumarin 7-hydroxylation. However, Nicotelline does not show inhibitory effects at a concentration of 300 μM. It serves as a tracer and biomarker for particulate matter (PM) originating from tobacco smoke [1] [2]. |
| Target activity | CYP26:≥300 μM (Ki) |
| Synonyms | Nicotellin |
| molecular weight | 233.27 |
| Molecular formula | C15H11N3 |
| CAS | 494-04-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |